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Beyond Cartilage Repair: The Role of the Osteochondral Unit in Joint Health and Disease.
Lepage, Sarah I M; Robson, Naomi; Gilmore, Hillary; Davis, Ola; Hooper, Allyssa; St John, Stephanie; Kamesan, Vashine; Gelis, Paul; Carvajal, Diana; Hurtig, Mark; Koch, Thomas G.
Afiliação
  • Lepage SIM; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • Robson N; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • Gilmore H; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • Davis O; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • Hooper A; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • St John S; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • Kamesan V; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • Gelis P; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • Carvajal D; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
  • Hurtig M; 2 Department of Clinical Studies, University of Guelph, Guelph, Canada.
  • Koch TG; 1 Department of Biomedical Sciences, University of Guelph, Guelph, Canada.
Tissue Eng Part B Rev ; 25(2): 114-125, 2019 04.
Article em En | MEDLINE | ID: mdl-30638141
ABSTRACT
IMPACT STATEMENT In this comprehensive review, we are providing a holistic overview of osteochondral tissue development, disease, pain localization, as well as structural evaluation and current repair strategies. This review is intended to serve as a broad introduction to this multidisciplinary research area. It is a thorough examination of the biological aspects of the osteochondral unit from a tissue engineering perspective, highlighting the importance of the subchondral bone in chondral and osteochondral lesion repair and pain relief.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osso e Ossos / Cartilagem Articular / Condrócitos / Engenharia Tecidual / Traumatismos do Joelho Limite: Animals / Humans Idioma: En Revista: Tissue Eng Part B Rev Assunto da revista: BIOTECNOLOGIA / HISTOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osso e Ossos / Cartilagem Articular / Condrócitos / Engenharia Tecidual / Traumatismos do Joelho Limite: Animals / Humans Idioma: En Revista: Tissue Eng Part B Rev Assunto da revista: BIOTECNOLOGIA / HISTOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá