The long noncoding RNA HOTTIP promotes breast cancer cell migration, invasiveness, and epithelial-mesenchymal transition via the Wnt-ß-catenin signaling pathway.

Han, Sijia; Jin, Xiaoming; Liu, Zhen; Xing, Fei; Han, Ye; Yu, Xiaopeng; He, Guijin; Qiu, Fang

Han, Sijia; Jin, Xiaoming; Liu, Zhen; Xing, Fei; Han, Ye; Yu, Xiaopeng; He, Guijin; Qiu, Fang.

Afiliação

Han S; Department of Breast Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Jin X; Department of Endocrinology, Northern Theater Command Airforce Hospital of Chinese PLA, Shenyang 110042, People's Republic of China.
Liu Z; Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Xing F; Department of Breast Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Han Y; Department of Breast Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Yu X; Department of Breast Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
He G; Department of Breast Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.
Qiu F; Department of Breast Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China.

Biochem Cell Biol ; 97(5): 655-664, 2019 10.

Article em En | MEDLINE | ID: mdl-30676763

Assuntos

Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Movimento Celular; Transição Epitelial-Mesenquimal; RNA Longo não Codificante/metabolismo; Via de Sinalização Wnt; Animais; Neoplasias da Mama/genética; Feminino; Humanos; Neoplasias Mamárias Experimentais/genética; Neoplasias Mamárias Experimentais/metabolismo; Neoplasias Mamárias Experimentais/patologia; Camundongos; Camundongos Nus; Pessoa de Meia-Idade; RNA Longo não Codificante/genética; Células Tumorais Cultivadas; beta Catenina/metabolismo

Palavras-chave

HOTTIP; Wntß-catenin pathway; breast cancer; cancer du sein; cell migration/invasiveness; migration/invasion cellulaire; voie Wntß-caténine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Movimento Celular / Transição Epitelial-Mesenquimal / Via de Sinalização Wnt / RNA Longo não Codificante Limite: Animals / Female / Humans / Middle aged Idioma: En Revista: Biochem Cell Biol Assunto da revista: BIOQUIMICA Ano de publicação: 2019 Tipo de documento: Article

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