Adjunctive Perampanel Oral Suspension in Pediatric Patients From &#8805;2 to <12 Years of Age With Epilepsy: Pharmacokinetics, Safety, Tolerability, and Efficacy.

Renfroe, J Ben; Mintz, Mark; Davis, Ronald; Ferreira, Jose; Dispoto, Sharon; Ferry, Jim; Umetsu, Yuko; Rege, Bhaskar; Majid, Oneeb; Hussein, Ziad; Laurenza, Antonio

Adjunctive Perampanel Oral Suspension in Pediatric Patients From ≥2 to <12 Years of Age With Epilepsy: Pharmacokinetics, Safety, Tolerability, and Efficacy.

Renfroe, J Ben; Mintz, Mark; Davis, Ronald; Ferreira, Jose; Dispoto, Sharon; Ferry, Jim; Umetsu, Yuko; Rege, Bhaskar; Majid, Oneeb; Hussein, Ziad; Laurenza, Antonio.

Afiliação

Renfroe JB; 1 Child Neurology Center of Northwest Florida, Gulf Breeze, FL, USA.
Mintz M; 2 The Center for Neurological and Neurodevelopmental Health (CNNH) and the Clinical Research Center of New Jersey (CRCNJ), Voorhees, NJ, USA.
Davis R; 3 Pediatric Neurology, P.A., and Epilepsy Center of Central Florida, Orlando, FL, USA.
Ferreira J; 4 Department of Pediatrics, University of South Florida, School of Medicine, Tampa, FL, USA.
Dispoto S; 5 Pediatric Neurology, St. Joseph's Children's Hospital, Tampa, FL, USA.
Ferry J; 6 Pediatric Epilepsy and Neurology Specialists (PENS), Tampa, FL, USA.
Umetsu Y; 7 Eisai Neurology Business Group, Eisai Inc., Woodcliff Lake, NJ, USA.
Rege B; 8 Eisai Clinical Pharmacology, Eisai Inc., Woodcliff Lake, NJ, USA.
Majid O; 9 Eisai Co., Ltd., Tokyo, Japan.
Hussein Z; 10 Formerly: Eisai Clinical Pharmacology, Eisai Inc., Woodcliff Lake, NJ, USA.
Laurenza A; 11 Eisai Clinical Pharmacology, Eisai Ltd., European Knowledge Centre, Hatfield, Hertfordshire, United Kingdom.

J Child Neurol ; 34(5): 284-294, 2019 04.

Article em En | MEDLINE | ID: mdl-30739576

Assuntos

Anticonvulsivantes/uso terapêutico; Epilepsia/tratamento farmacológico; Piridonas/uso terapêutico; Administração Oral; Adolescente; Anticonvulsivantes/efeitos adversos; Anticonvulsivantes/farmacocinética; Criança; Pré-Escolar; Quimioterapia Combinada; Humanos; Nitrilas; Projetos Piloto; Piridonas/efeitos adversos; Piridonas/farmacocinética; Convulsões/tratamento farmacológico; Resultado do Tratamento

Palavras-chave

antiepileptic drugs; efficacy; epilepsy; pediatric; seizures

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridonas / Epilepsia / Anticonvulsivantes Tipo de estudo: Clinical_trials Limite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: J Child Neurol Assunto da revista: NEUROLOGIA / PEDIATRIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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