The first identification of nesfatin-1-expressing neurons in the human bed nucleus of the stria terminalis.
J Neural Transm (Vienna)
; 126(3): 349-355, 2019 03.
Article
em En
| MEDLINE
| ID: mdl-30770997
ABSTRACT
Neuropeptides are involved in various brain activities being able to control a wide spectrum of higher mental functions. The purpose of this concise structural investigation was to detect the possible immunoreactivity of the novel multifunctional neuropeptide nesfatin-1 within the human bed nucleus of the stria terminalis (BNST). The BNST is involved in the mechanism of fear learning, integration of stress and reward circuits, and pathogenesis of addiction. Nesfatin-1-expressing neurons were identified for the first time in several regions of the BNST using both immunohistochemical and fluorescent methods. This may implicate a potential contribution of this neuropeptide to the BNST-related mechanisms of stress/reward responses in the human brain.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Núcleos Septais
/
Nucleobindinas
/
Neurônios
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
J Neural Transm (Vienna)
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Polônia