The effects of pulmonary valve replacement on QRS duration in repaired tetralogy of Fallot patients with pulmonary regurgitation.
J Electrocardiol
; 54: 36-39, 2019.
Article
em En
| MEDLINE
| ID: mdl-30856514
ABSTRACT
INTRODUCTION:
Chronic pulmonary regurgitation (PR) following surgical correction in Tetralogy of Fallot (TOF) leads to right ventricular (RV) dysfunction, arrhythmias and sudden cardiac death (SCD). Pulmonary valve replacement (PVR) decreases PR and improves RV function, but data regarding QRS duration reduction remain scarce.METHODS:
All adult TOF patients undergoing transcatheter PVR or surgical PVR from 2010 to 2016 were included. Clinical characteristics and QRS duration were measured and compared to post-intervention QRS duration using an institutional software and manually verified. Significantly wide QRS was defined as QRS >140â¯ms.RESULTS:
Of 133 PVR patients, 85 had TOF and 27 (21.1%) had QRSâ¯>â¯140â¯ms (14 transcatheter, 13 surgical) and were included in this analysis. A 6â¯ms decrease in QRS duration was seen at 3-year follow-up (168.0⯱â¯3.5â¯ms vs. 161.8⯱â¯3.5â¯ms, pâ¯=â¯.04). There was a significant decrease in the median RV size (defined as RV/LV diameter ratio) pre-intervention to 3-year post-intervention (0.96 vs 0.89, pâ¯=â¯.03). The median PR decreased significantly from moderate-severe to mild post-intervention (pâ¯<â¯.0001).CONCLUSIONS:
Replacement of the pulmonary valve in high risk TOF patients reduces QRS duration at 3â¯years. Further study is needed to assess whether this QRS duration reduction may identify patients at lower risk of ventricular arrhythmias.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arritmias Cardíacas
/
Valva Pulmonar
/
Insuficiência da Valva Pulmonar
/
Tetralogia de Fallot
/
Implante de Prótese de Valva Cardíaca
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Electrocardiol
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Estados Unidos