Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses.

Benayoun, Bérénice A; Pollina, Elizabeth A; Singh, Param Priya; Mahmoudi, Salah; Harel, Itamar; Casey, Kerriann M; Dulken, Ben W; Kundaje, Anshul; Brunet, Anne

Benayoun, Bérénice A; Pollina, Elizabeth A; Singh, Param Priya; Mahmoudi, Salah; Harel, Itamar; Casey, Kerriann M; Dulken, Ben W; Kundaje, Anshul; Brunet, Anne.

Afiliação

Benayoun BA; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Pollina EA; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Singh PP; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Mahmoudi S; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Harel I; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Casey KM; Department of Comparative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
Dulken BW; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Kundaje A; Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Brunet A; Department of Computer Science, Stanford University, Stanford, California 94305, USA.

Genome Res ; 29(4): 697-709, 2019 04.

Article em En | MEDLINE | ID: mdl-30858345

Assuntos

Envelhecimento/genética; Epigênese Genética; Imunidade Inata/genética; Transcriptoma; Animais; Código das Histonas; Inflamação/genética; Interferons/genética; Masculino; Camundongos; Camundongos Endogâmicos C57BL

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Epigênese Genética / Transcriptoma / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Genome Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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