Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition.

Sottile, Rosa; Federico, Giorgia; Garofalo, Cinzia; Tallerico, Rossana; Faniello, Maria Concetta; Quaresima, Barbara; Cristiani, Costanza Maria; Di Sanzo, Maddalena; Cuda, Gianni; Ventura, Valeria; Wagner, Arnika Kathleen; Contrò, Gianluca; Perrotti, Nicola; Gulletta, Elio; Ferrone, Soldano; Kärre, Klas; Costanzo, Francesco Saverio; Carlomagno, Francesca; Carbone, Ennio

Sottile, Rosa; Federico, Giorgia; Garofalo, Cinzia; Tallerico, Rossana; Faniello, Maria Concetta; Quaresima, Barbara; Cristiani, Costanza Maria; Di Sanzo, Maddalena; Cuda, Gianni; Ventura, Valeria; Wagner, Arnika Kathleen; Contrò, Gianluca; Perrotti, Nicola; Gulletta, Elio; Ferrone, Soldano; Kärre, Klas; Costanzo, Francesco Saverio; Carlomagno, Francesca; Carbone, Ennio.

Afiliação

Sottile R; Tumor Immunology and Immunopathology Laboratory, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Federico G; Department of Microbiology, Cell and Tumor Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
Garofalo C; Department of Molecular Medicine and Medical Biotechnologies Federico II University, Naples, Italy.
Tallerico R; Tumor Immunology and Immunopathology Laboratory, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Faniello MC; Tumor Immunology and Immunopathology Laboratory, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Quaresima B; Research Center of Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Cristiani CM; Research Center of Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Di Sanzo M; Tumor Immunology and Immunopathology Laboratory, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Cuda G; Research Center of Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Ventura V; Laboratory of Proteomics, Research Center of Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Wagner AK; Tumor Immunology and Immunopathology Laboratory, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Contrò G; Division of Clinical Pathology, Department of Health Sciences, Magna Graecia University, Catanzaro, Italy.
Perrotti N; Department of Microbiology, Cell and Tumor Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
Gulletta E; Department of Health Sciences, University of Catanzaro Magna Graecia, Catanzaro, Italy.
Ferrone S; Department of Health Sciences, University of Catanzaro Magna Graecia, Catanzaro, Italy.
Kärre K; Division of Clinical Pathology, Department of Health Sciences, Magna Graecia University, Catanzaro, Italy.
Costanzo FS; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Carlomagno F; Department of Microbiology, Cell and Tumor Biology (MTC), Karolinska Institutet, Stockholm, Sweden.
Carbone E; Research Center of Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.

Front Immunol ; 10: 224, 2019.

Article em En | MEDLINE | ID: mdl-30873154

Assuntos

Apoferritinas/metabolismo; Citotoxicidade Imunológica/imunologia; Antígenos de Histocompatibilidade Classe I/imunologia; Ferro/metabolismo; Células Matadoras Naturais/imunologia; Animais; Apoferritinas/genética; Linhagem Celular Tumoral; Células Cultivadas; Citotoxicidade Imunológica/genética; Desferroxamina/farmacologia; Embrião de Mamíferos/citologia; Fibroblastos/citologia; Fibroblastos/imunologia; Fibroblastos/metabolismo; Expressão Gênica/efeitos dos fármacos; Células HeLa; Antígenos de Histocompatibilidade Classe I/genética; Antígenos de Histocompatibilidade Classe I/metabolismo; Humanos; Interferon gama/farmacologia; Células K562; Células Matadoras Naturais/metabolismo; Células MCF-7; Macrófagos/imunologia; Macrófagos/metabolismo; Camundongos Endogâmicos C57BL; Camundongos Knockout; Coativadores de Receptor Nuclear/genética; Coativadores de Receptor Nuclear/metabolismo; Interferência de RNA; Sideróforos/farmacologia

Palavras-chave

HLA; IFNÎ³; MHC-I; NK cells; STAT1; iron

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoferritinas / Células Matadoras Naturais / Antígenos de Histocompatibilidade Classe I / Citotoxicidade Imunológica / Ferro Limite: Animals / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália

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