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Synthesis and evaluation of haloperidol ester prodrugs metabolically activated by human carboxylesterase.
Takahashi, Masato; Uehara, Tomoki; Nonaka, Minori; Minagawa, Yuka; Yamazaki, Riona; Haba, Masami; Hosokawa, Masakiyo.
Afiliação
  • Takahashi M; Faculty of Pharmacy, Chiba Institute of Science, 15-8, Shiomi-cho, Choshi, Chiba 288-0025, Japan. Electronic address: matakahashi@cis.ac.jp.
  • Uehara T; Faculty of Pharmacy, Chiba Institute of Science, 15-8, Shiomi-cho, Choshi, Chiba 288-0025, Japan.
  • Nonaka M; Faculty of Pharmacy, Chiba Institute of Science, 15-8, Shiomi-cho, Choshi, Chiba 288-0025, Japan.
  • Minagawa Y; Faculty of Pharmacy, Chiba Institute of Science, 15-8, Shiomi-cho, Choshi, Chiba 288-0025, Japan.
  • Yamazaki R; Faculty of Pharmacy, Chiba Institute of Science, 15-8, Shiomi-cho, Choshi, Chiba 288-0025, Japan.
  • Haba M; Faculty of Pharmacy, Chiba Institute of Science, 15-8, Shiomi-cho, Choshi, Chiba 288-0025, Japan.
  • Hosokawa M; Faculty of Pharmacy, Chiba Institute of Science, 15-8, Shiomi-cho, Choshi, Chiba 288-0025, Japan.
Eur J Pharm Sci ; 132: 125-131, 2019 Apr 30.
Article em En | MEDLINE | ID: mdl-30878380
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Carboxilesterase / Haloperidol / Microssomos Limite: Humans Idioma: En Revista: Eur J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Carboxilesterase / Haloperidol / Microssomos Limite: Humans Idioma: En Revista: Eur J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article