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RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals.
Lesch, Markus; Luckner, Madlen; Meyer, Michael; Weege, Friderike; Gravenstein, Isabella; Raftery, Martin; Sieben, Christian; Martin-Sancho, Laura; Imai-Matsushima, Aki; Welke, Robert-William; Frise, Rebecca; Barclay, Wendy; Schönrich, Günther; Herrmann, Andreas; Meyer, Thomas F; Karlas, Alexander.
Afiliação
  • Lesch M; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
  • Luckner M; Steinbeis Innovation Center for Systems Biomedicine, Falkensee, Germany.
  • Meyer M; Group of Molecular Biophysics, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.
  • Weege F; Steinbeis Innovation Center for Systems Biomedicine, Falkensee, Germany.
  • Gravenstein I; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
  • Raftery M; Steinbeis Innovation Center for Systems Biomedicine, Falkensee, Germany.
  • Sieben C; Institute of Virology, Charité University Medicine, Berlin, Germany.
  • Martin-Sancho L; Group of Molecular Biophysics, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.
  • Imai-Matsushima A; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
  • Welke RW; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
  • Frise R; Group of Molecular Biophysics, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.
  • Barclay W; Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, United Kingdom.
  • Schönrich G; Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, United Kingdom.
  • Herrmann A; Institute of Virology, Charité University Medicine, Berlin, Germany.
  • Meyer TF; Group of Molecular Biophysics, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.
  • Karlas A; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
PLoS Pathog ; 15(3): e1007601, 2019 03.
Article em En | MEDLINE | ID: mdl-30883607
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Orthomyxoviridae / Replicação Viral Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Orthomyxoviridae / Replicação Viral Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha