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Targeting Multiple Myeloma with AMG 424, a Novel Anti-CD38/CD3 Bispecific T-cell-recruiting Antibody Optimized for Cytotoxicity and Cytokine Release.
Zuch de Zafra, Christina L; Fajardo, Flordeliza; Zhong, Wendy; Bernett, Matthew J; Muchhal, Umesh S; Moore, Gregory L; Stevens, Jennitte; Case, Ryan; Pearson, Joshua T; Liu, Siyuan; McElroy, Patricia L; Canon, Jude; Desjarlais, John R; Coxon, Angela; Balazs, Mercedesz; Nolan-Stevaux, Olivier.
Afiliação
  • Zuch de Zafra CL; Comparative Biology and Safety Sciences, Amgen South San Francisco, California.
  • Fajardo F; Amgen Research, Thousand Oaks, California.
  • Zhong W; Amgen Research, Thousand Oaks, California.
  • Bernett MJ; Department of Oncology-Immunology Research, Amgen, South San Francisco and Amgen Thousand Oaks, California.
  • Muchhal US; Amgen Research, Thousand Oaks, California.
  • Moore GL; Department of Oncology-Immunology Research, Amgen, South San Francisco and Amgen Thousand Oaks, California.
  • Stevens J; Xencor, Monrovia, California.
  • Case R; Xencor, Monrovia, California.
  • Pearson JT; Xencor, Monrovia, California.
  • Liu S; Amgen Research, Thousand Oaks, California.
  • McElroy PL; Therapeutic Discovery, Amgen, Thousand Oaks, California.
  • Canon J; Amgen Research, Thousand Oaks, California.
  • Desjarlais JR; Discovery Attribute Sciences, South San Francisco, California.
  • Coxon A; Amgen Research, Thousand Oaks, California.
  • Balazs M; Pharmacokinetics and Drug Metabolism, Amgen, South San Francisco, California.
  • Nolan-Stevaux O; Amgen Research, Thousand Oaks, California.
Clin Cancer Res ; 25(13): 3921-3933, 2019 07 01.
Article em En | MEDLINE | ID: mdl-30918018
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Citocinas / Anticorpos Biespecíficos / Antineoplásicos Imunológicos / Citotoxicidade Celular Dependente de Anticorpos / Mieloma Múltiplo Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Citocinas / Anticorpos Biespecíficos / Antineoplásicos Imunológicos / Citotoxicidade Celular Dependente de Anticorpos / Mieloma Múltiplo Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article