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Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer.
Wirbel, Jakob; Pyl, Paul Theodor; Kartal, Ece; Zych, Konrad; Kashani, Alireza; Milanese, Alessio; Fleck, Jonas S; Voigt, Anita Y; Palleja, Albert; Ponnudurai, Ruby; Sunagawa, Shinichi; Coelho, Luis Pedro; Schrotz-King, Petra; Vogtmann, Emily; Habermann, Nina; Niméus, Emma; Thomas, Andrew M; Manghi, Paolo; Gandini, Sara; Serrano, Davide; Mizutani, Sayaka; Shiroma, Hirotsugu; Shiba, Satoshi; Shibata, Tatsuhiro; Yachida, Shinichi; Yamada, Takuji; Waldron, Levi; Naccarati, Alessio; Segata, Nicola; Sinha, Rashmi; Ulrich, Cornelia M; Brenner, Hermann; Arumugam, Manimozhiyan; Bork, Peer; Zeller, Georg.
Afiliação
  • Wirbel J; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Pyl PT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Kartal E; Division of Surgery, Oncology and Pathology, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden.
  • Zych K; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Kashani A; Molecular Medicine Partnership Unit, Heidelberg, Germany.
  • Milanese A; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Fleck JS; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Voigt AY; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Palleja A; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Ponnudurai R; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Sunagawa S; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
  • Coelho LP; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Schrotz-King P; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Vogtmann E; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Habermann N; Department of Biology, ETH Zürich, Zürich, Switzerland.
  • Niméus E; Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Thomas AM; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China.
  • Manghi P; Division of Preventive Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany.
  • Gandini S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
  • Serrano D; Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
  • Mizutani S; Division of Surgery, Oncology and Pathology, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden.
  • Shiroma H; Division of Surgery, Department of Clinical Sciences Lund, Faculty of Medicine, Skane University Hospital, Lund, Sweden.
  • Shiba S; Department CIBIO, University of Trento, Trento, Italy.
  • Shibata T; Biochemistry Department, Chemistry Institute, University of São Paulo, São Paulo, Brazil.
  • Yachida S; Department CIBIO, University of Trento, Trento, Italy.
  • Yamada T; IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Waldron L; IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Naccarati A; School of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
  • Segata N; Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan.
  • Sinha R; School of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
  • Ulrich CM; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
  • Brenner H; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
  • Arumugam M; Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Bork P; Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.
  • Zeller G; Department of Cancer Genome Informatics, Graduate School of Medicine/Faculty of Medicine, Osaka University, Osaka, Japan.
Nat Med ; 25(4): 679-689, 2019 04.
Article em En | MEDLINE | ID: mdl-30936547
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Metagenoma / Fezes / Microbioma Gastrointestinal Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Metagenoma / Fezes / Microbioma Gastrointestinal Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha