Structural insights into the mechanism of single domain VHH antibody binding to cortisol.

Ding, Lulu; Wang, Ziying; Zhong, Peiyu; Jiang, He; Zhao, Zhixuan; Zhang, Yiran; Ren, Zhen; Ding, Yu

Ding, Lulu; Wang, Ziying; Zhong, Peiyu; Jiang, He; Zhao, Zhixuan; Zhang, Yiran; Ren, Zhen; Ding, Yu.

Afiliação

Ding L; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Wang Z; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Zhong P; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Jiang H; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Zhao Z; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Zhang Y; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Ren Z; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Ding Y; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.

FEBS Lett ; 593(11): 1248-1256, 2019 06.

Article em En | MEDLINE | ID: mdl-31049949

Assuntos

Hidrocortisona/metabolismo; Anticorpos de Domínio Único/química; Animais; Sítios de Ligação; Humanos; Hidrocortisona/química; Ligação Proteica; Anticorpos de Domínio Único/metabolismo

Palavras-chave

VHH antibody; cortisol; nanobody; structure

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrocortisona / Anticorpos de Domínio Único Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: FEBS Lett Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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