Application of tRNS to improve multiple sclerosis fatigue: a pilot, single-blind, sham-controlled study.
J Neural Transm (Vienna)
; 126(6): 795-799, 2019 06.
Article
em En
| MEDLINE
| ID: mdl-31054015
ABSTRACT
We evaluated the effects of transcranial random noise stimulation (tRNS) on fatigue in 17 subjects with relapsing-remitting multiple sclerosis with low physical disability. Two different patient groups underwent real or sham stimulation for 10 days, targeting the primary motor cortex of the dominant side or contralateral to the most compromised limb. In the 'real group', beneficial effects were observed using the Modified Fatigue Impact Scale (p = 0.04; physical subscale p = 0.03), the subscales 'change in health' (p = 0.006) and 'role limitations due to physical problems' (p = 0.001) of the Multiple Sclerosis Quality of Life-54, and by assessing the patient impression of perceived fatigue (p = 0.005).
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Avaliação de Resultados em Cuidados de Saúde
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Esclerose Múltipla Recidivante-Remitente
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Fadiga
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Estimulação Transcraniana por Corrente Contínua
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Córtex Motor
Tipo de estudo:
Clinical_trials
/
Etiology_studies
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
J Neural Transm (Vienna)
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Itália