Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis.

Gucek, Alenka; Gandasi, Nikhil R; Omar-Hmeadi, Muhmmad; Bakke, Marit; Døskeland, Stein O; Tengholm, Anders; Barg, Sebastian

Gucek, Alenka; Gandasi, Nikhil R; Omar-Hmeadi, Muhmmad; Bakke, Marit; Døskeland, Stein O; Tengholm, Anders; Barg, Sebastian.

Afiliação

Gucek A; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Gandasi NR; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Omar-Hmeadi M; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Bakke M; Department of Biomedicine, University of Bergen, Bergen, Norway.
Døskeland SO; Department of Biomedicine, University of Bergen, Bergen, Norway.
Tengholm A; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Barg S; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.

Elife ; 82019 05 20.

Article em En | MEDLINE | ID: mdl-31099751

Assuntos

AMP Cíclico/metabolismo; Exocitose; Fatores de Troca do Nucleotídeo Guanina/metabolismo; Insulina/metabolismo; Animais; Proteínas de Transporte/metabolismo; Dinamina I/metabolismo; Humanos; Camundongos Knockout

Palavras-chave

Epac2; GLP-1; cell biology; exendin-4; exocytosis; fusion pore; hormone secretion; human; human biology; medicine; mouse

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: AMP Cíclico / Fatores de Troca do Nucleotídeo Guanina / Exocitose / Insulina Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suécia

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