Testicular Cancer in a Lung Transplant Patient With Cystic Fibrosis: A Case Report.
Transplant Proc
; 51(4): 1293-1295, 2019 May.
Article
em En
| MEDLINE
| ID: mdl-31101217
ABSTRACT
BACKGROUND:
Cystic fibrosis (CF) is one of the most common genetic disorders that develops from a mutation of the cystic fibrosis transmembrane regulator gene. Patients with CF are known to be at risk for malignancies, and lung transplantation-associated immunosuppression further increases this risk. CASE REPORT We describe a case of a 29-year-old male patient with CF who developed testicular cancer 14 months after a lung transplantation. Immunosuppressive therapy included antithymocyte globulin induction and tacrolimus, mycophenolate, and prednisolone maintenance therapy as compared to standard alemtuzumab induction, followed by tacrolimus and prednisolone, as used in our center. He underwent semicastration and refused chemotherapy. Immunosuppressive treatment was changed to tacrolimus, everolimus, and prednisolone, which did not influence excellent graft function. This case report highlights the importance of uro-oncological observation of patients with CF following lung transplantations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Testiculares
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Terapia de Imunossupressão
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Transplante de Pulmão
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Neoplasias Embrionárias de Células Germinativas
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Fibrose Cística
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Transplant Proc
Ano de publicação:
2019
Tipo de documento:
Article