Multicomponent reactions (MCRs): a useful access to the synthesis of benzo-fused γ-lactams.
Beilstein J Org Chem
; 15: 1065-1085, 2019.
Article
em En
| MEDLINE
| ID: mdl-31164944
ABSTRACT
Benzo-fused γ-lactam rings such as isoindolin-2-ones and 2-oxindoles are part of the structure of many pharmaceutically active molecules. They can be often synthesized by means of multicomponent approaches and recent contributions in this field are summarized in this review. Clear advantages of these methods include the efficiency in saving raw materials and working time. However, there is still a need of new catalytic systems to allow the enantioselective preparation of these heterocycles by multicomponent reactions.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Beilstein J Org Chem
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Espanha