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AMPK directly activates mTORC2 to promote cell survival during acute energetic stress.
Kazyken, Dubek; Magnuson, Brian; Bodur, Cagri; Acosta-Jaquez, Hugo A; Zhang, Deqiang; Tong, Xin; Barnes, Tammy M; Steinl, Gabrielle K; Patterson, Nicole E; Altheim, Christopher H; Sharma, Naveen; Inoki, Ken; Cartee, Gregory D; Bridges, Dave; Yin, Lei; Riddle, Steven M; Fingar, Diane C.
Afiliação
  • Kazyken D; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Magnuson B; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Bodur C; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Acosta-Jaquez HA; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Zhang D; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Tong X; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Barnes TM; Department of Internal Medicine and Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Steinl GK; Department of Internal Medicine and Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Patterson NE; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Altheim CH; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Sharma N; School of Kinesiology, Department of Molecular and Integrative Physiology, Institute of Gerontology, University of Michigan, Ann Arbor, MI 48109-2200, USA.
  • Inoki K; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Cartee GD; School of Kinesiology, Department of Molecular and Integrative Physiology, Institute of Gerontology, University of Michigan, Ann Arbor, MI 48109-2200, USA.
  • Bridges D; Department of Nutritional Sciences, University of Michigan, Ann Arbor, MI 48109-2200, USA.
  • Yin L; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.
  • Riddle SM; Illumina, Madison, WI 53704, USA.
  • Fingar DC; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA. dfingar@umich.edu.
Sci Signal ; 12(585)2019 06 11.
Article em En | MEDLINE | ID: mdl-31186373
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Apoptose / Hepatócitos / Metabolismo Energético / Proteínas Quinases Ativadas por AMP / Alvo Mecanístico do Complexo 2 de Rapamicina Limite: Animals Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Apoptose / Hepatócitos / Metabolismo Energético / Proteínas Quinases Ativadas por AMP / Alvo Mecanístico do Complexo 2 de Rapamicina Limite: Animals Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos