Pancreatic cancer in bloom syndrome.
SAGE Open Med Case Rep
; 7: 2050313X19855587, 2019.
Article
em En
| MEDLINE
| ID: mdl-31210938
ABSTRACT
Bloom syndrome is a rare autosomal recessive disorder characterized by distinct physical features, such as short stature, genomic instability, and predisposition to numerous cancers. The BLM gene encodes for the RecQ helicase that plays an important role in genome editing, maintenance, and stability. Mutations in the BLM gene cause genomic instability that exposes the carriers to a variety of cancers, and in particular hematological and gastrointestinal cancers. Herein, we report the first case of pancreatic cancer in a 32-year-old patient with bloom syndrome.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
SAGE Open Med Case Rep
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Israel