19âG aspiration needle versus 19âG core biopsy needle for endoscopic ultrasound-guided liver biopsy: a prospective randomized trial.
Endoscopy
; 51(11): 1059-1065, 2019 11.
Article
em En
| MEDLINE
| ID: mdl-31342474
ABSTRACT
BACKGROUND:
Endoscopic ultrasound-guided liver biopsy (EUS-LB) is a safe and effective method for accomplishing parenchymal liver biopsy. The aim of this study was to compare a 19 G aspiration needle (FNA) with a 19 G Franseen-tip core biopsy needle (FNB) for EUS-LB.METHODS:
This was a prospective, parallel group, randomized trial comparing the tissue yields and adequacy of a 19âG FNA needle vs. a 19âG FNB needle for EUS-LB. The primary outcome was length of the longest piece of liver core specimen. Secondary outcomes were aggregate specimen length, number of complete portal triads (CPTs), and adverse events. One transgastric pass and one transduodenal pass were performed with the same needle in each patient. Specimen lengths were measured before and after histological processing.RESULTS:
40 patients referred for EUS-LB were randomized to either the FNA group (nâ=â20) or the FNB group (nâ=â20). Both groups had similar patient characteristics. FNB biopsies yielded longer mean (standard deviation) specimen lengths (pre-processing mean 2.09âcm [0.41] vs. mean 1.47âcm [0.46], and post-processing mean 1.78âcm [0.66] vs. mean 1.05âcm [0.42]; both Pâ<â0.001), a longer aggregate specimen length (pre-processing mean 15.78âcm [5.19] vs. 10.89âcm [4.38]; Pâ=â0.003), and more CPTs (mean 42.6 25 vs 18.1 [9.3]; Pâ<â0.001) compared with the FNA needle. There were no severe adverse events or difference in adverse event rate between the two needles. Post-biopsy pain was noted in 37.5â%.CONCLUSION:
EUS-LB using the FNB needle delivered longer liver biopsy specimens with more CPTs than the regular (non-core) needle.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ultrassonografia Doppler
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Endossonografia
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Aspiração por Agulha Fina Guiada por Ultrassom Endoscópico
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Fígado
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Hepatopatias
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Endoscopy
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Estados Unidos