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Synthesis and evaluation of 2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione derivatives as Mnk inhibitors.
Abdelaziz, Ahmed M; Basnet, Sunita K C; Islam, Saiful; Li, Manjun; Tadesse, Solomon; Albrecht, Hugo; Gerber, Cobus; Yu, Mingfeng; Wang, Shudong.
Afiliação
  • Abdelaziz AM; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia.
  • Basnet SKC; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia.
  • Islam S; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia.
  • Li M; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia.
  • Tadesse S; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia.
  • Albrecht H; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia.
  • Gerber C; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia.
  • Yu M; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia. Electronic address: mingfeng.yu@unisa.edu.au.
  • Wang S; Centre for Drug Discovery and Development, Cancer Research Institute, and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia 5001, Australia. Electronic address: shudong.wang@unisa.edu.au.
Bioorg Med Chem Lett ; 29(18): 2650-2654, 2019 09 15.
Article em En | MEDLINE | ID: mdl-31362920
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Compostos de Espiro / Cicloexanos / Inibidores de Proteínas Quinases / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Compostos de Espiro / Cicloexanos / Inibidores de Proteínas Quinases / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália