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New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Design, synthesis, biological activity and structure-activity relationships.
Ribeiro, Daniela; Proença, Carina; Varela, Carla; Janela, João; Tavares da Silva, Elisiário J; Fernandes, Eduarda; Roleira, Fernanda M F.
Afiliação
  • Ribeiro D; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
  • Proença C; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
  • Varela C; Pharmaceutical Chemistry Laboratory, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal; CIEPQPF Centre for Chemical Processes Engineering and Forest Products, University of Coimbra, 3030-790 Coimbra, Portugal.
  • Janela J; Pharmaceutical Chemistry Laboratory, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.
  • Tavares da Silva EJ; Pharmaceutical Chemistry Laboratory, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal; CIEPQPF Centre for Chemical Processes Engineering and Forest Products, University of Coimbra, 3030-790 Coimbra, Portugal.
  • Fernandes E; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal. Electronic address: egracas@ff.up.pt.
  • Roleira FMF; Pharmaceutical Chemistry Laboratory, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal; CIEPQPF Centre for Chemical Processes Engineering and Forest Products, University of Coimbra, 3030-790 Coimbra, Portugal. Electronic address: froleira@ff.uc.pt.
Bioorg Chem ; 91: 103179, 2019 10.
Article em En | MEDLINE | ID: mdl-31404794
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Desenho de Fármacos / Cinamatos / Ciclo-Oxigenase 1 / Ciclo-Oxigenase 2 / Inibidores de Ciclo-Oxigenase 2 / Amidas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Portugal
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Desenho de Fármacos / Cinamatos / Ciclo-Oxigenase 1 / Ciclo-Oxigenase 2 / Inibidores de Ciclo-Oxigenase 2 / Amidas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Portugal