Multilab evaluation of delafloxacin MIC Test Strip against Gram-negative and Gram-positive organisms.
Diagn Microbiol Infect Dis
; 95(3): 114868, 2019 Nov.
Article
em En
| MEDLINE
| ID: mdl-31447245
ABSTRACT
The performance of the delafloxacin MIC Test Strip (MTS) was evaluated. Three testing sites collected/tested clinical isolates, and 1 site tested challenge isolates that together total 224â¯S. aureus, 36â¯S. haemolyticus, 23â¯S. lugdunensis, 105 E. faecalis, 308 Enterobacteriales, and 140 P. aeruginosa. MIC testing was performed by broth microdilution (BMD) and MTS. Each site also tested 20 common isolates in triplicate on 3 days by MTS and 20 replicates of 4 QC strains by MTS and BMD. MTS results for consolidated clinical/challenge isolates were within 1 doubling dilution of the BMD MIC for 96.9% of S. aureus; 100% of S. haemolyticus, S. lugdunensis, and E. faecalis; 98.4% of Enterobacteriales; and 97.9% of P. aeruginosa. All reproducibility results were within 1 dilution of the modal MIC. All BMD and MTS results for the QC strains were within expected ranges. Overall, the delafloxacin MTS performed similar to BMD.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bactérias
/
Testes de Sensibilidade Microbiana
/
Fluoroquinolonas
/
Antibacterianos
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
En
Revista:
Diagn Microbiol Infect Dis
Ano de publicação:
2019
Tipo de documento:
Article