The subatomic resolution study of laccase inhibition by chloride and fluoride anions using single-crystal serial crystallography: insights into the enzymatic reaction mechanism.

Polyakov, Konstantin M; Gavryushov, Sergei; Fedorova, Tatiana V; Glazunova, Olga A; Popov, Alexander N

Polyakov, Konstantin M; Gavryushov, Sergei; Fedorova, Tatiana V; Glazunova, Olga A; Popov, Alexander N.

Afiliação

Polyakov KM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilova Street 32, Moscow 119991, Russian Federation.
Gavryushov S; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilova Street 32, Moscow 119991, Russian Federation.
Fedorova TV; A. N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Avenue 33/2, Moscow 119071, Russian Federation.
Glazunova OA; A. N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Avenue 33/2, Moscow 119071, Russian Federation.
Popov AN; ESRF - The European Synchrotron, CS40220, 38043 Grenoble CEDEX 9, France.

Acta Crystallogr D Struct Biol ; 75(Pt 9): 804-816, 2019 Sep 01.

Article em En | MEDLINE | ID: mdl-31478903

Assuntos

Cloretos/metabolismo; Cobre/metabolismo; Fluoretos/metabolismo; Lacase/química; Basidiomycota/enzimologia; Domínio Catalítico; Cristalografia por Raios X/métodos; Ligantes; Modelos Moleculares; Oxirredução; Oxigênio/metabolismo; Conformação Proteica; Imagem Individual de Molécula/métodos

Palavras-chave

enzymatic oxygen reduction; laccase inhibition; reaction mechanisms; single-crystal serial crystallography

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cloretos / Cobre / Lacase / Fluoretos Idioma: En Revista: Acta Crystallogr D Struct Biol Ano de publicação: 2019 Tipo de documento: Article

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