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Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence.
Harel, Michal; Ortenberg, Rona; Varanasi, Siva Karthik; Mangalhara, Kailash Chandra; Mardamshina, Mariya; Markovits, Ettai; Baruch, Erez N; Tripple, Victoria; Arama-Chayoth, May; Greenberg, Eyal; Shenoy, Anjana; Ayasun, Ruveyda; Knafo, Naama; Xu, Shihao; Anafi, Liat; Yanovich-Arad, Gali; Barnabas, Georgina D; Ashkenazi, Shira; Besser, Michal J; Schachter, Jacob; Bosenberg, Marcus; Shadel, Gerald S; Barshack, Iris; Kaech, Susan M; Markel, Gal; Geiger, Tamar.
Afiliação
  • Harel M; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Ortenberg R; Ella Lemelbaum Institute of Immuno-Oncology, Sheba Medical Center, Tel Hashomer 5265601, Israel; Department of Clinical Immunology and Microbiology, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Varanasi SK; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Mangalhara KC; Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Mardamshina M; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Markovits E; Ella Lemelbaum Institute of Immuno-Oncology, Sheba Medical Center, Tel Hashomer 5265601, Israel; Department of Clinical Immunology and Microbiology, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Baruch EN; Ella Lemelbaum Institute of Immuno-Oncology, Sheba Medical Center, Tel Hashomer 5265601, Israel; Department of Clinical Immunology and Microbiology, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Tripple V; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Arama-Chayoth M; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Greenberg E; Ella Lemelbaum Institute of Immuno-Oncology, Sheba Medical Center, Tel Hashomer 5265601, Israel.
  • Shenoy A; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Ayasun R; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Knafo N; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Xu S; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Anafi L; Institute of Pathology, Sheba Medical Center, Tel Hashomer 5265601, Israel.
  • Yanovich-Arad G; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Barnabas GD; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Ashkenazi S; Ella Lemelbaum Institute of Immuno-Oncology, Sheba Medical Center, Tel Hashomer 5265601, Israel; Department of Clinical Immunology and Microbiology, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Besser MJ; Ella Lemelbaum Institute of Immuno-Oncology, Sheba Medical Center, Tel Hashomer 5265601, Israel; Department of Clinical Immunology and Microbiology, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Schachter J; Ella Lemelbaum Institute of Immuno-Oncology, Sheba Medical Center, Tel Hashomer 5265601, Israel; The Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Bosenberg M; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA; Yale Comprehensive Cancer Center, New Haven, CT 06510, USA; Department of Dermatology, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Shadel GS; Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Barshack I; Institute of Pathology, Sheba Medical Center, Tel Hashomer 5265601, Israel; The Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Kaech SM; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Markel G; Ella Lemelbaum Institute of Immuno-Oncology, Sheba Medical Center, Tel Hashomer 5265601, Israel; Department of Clinical Immunology and Microbiology, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel. Electronic address: markel@post.tau.ac.il.
  • Geiger T; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel. Electronic address: geiger@tauex.tau.ac.il.
Cell ; 179(1): 236-250.e18, 2019 09 19.
Article em En | MEDLINE | ID: mdl-31495571
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Proteômica / Imunoterapia / Melanoma / Mitocôndrias Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Israel
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Proteômica / Imunoterapia / Melanoma / Mitocôndrias Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Israel