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PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia.
Konttinen, Henna; Cabral-da-Silva, Mauricio E Castro; Ohtonen, Sohvi; Wojciechowski, Sara; Shakirzyanova, Anastasia; Caligola, Simone; Giugno, Rosalba; Ishchenko, Yevheniia; Hernández, Damián; Fazaludeen, Mohammad Feroze; Eamen, Shaila; Budia, Mireia Gómez; Fagerlund, Ilkka; Scoyni, Flavia; Korhonen, Paula; Huber, Nadine; Haapasalo, Annakaisa; Hewitt, Alex W; Vickers, James; Smith, Grady C; Oksanen, Minna; Graff, Caroline; Kanninen, Katja M; Lehtonen, Sarka; Propson, Nicholas; Schwartz, Michael P; Pébay, Alice; Koistinaho, Jari; Ooi, Lezanne; Malm, Tarja.
Afiliação
  • Konttinen H; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Cabral-da-Silva MEC; School of Chemistry and Molecular Bioscience, Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.
  • Ohtonen S; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Wojciechowski S; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Shakirzyanova A; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Caligola S; Department of Computer Science, University of Verona, Verona 37134, Italy.
  • Giugno R; Department of Computer Science, University of Verona, Verona 37134, Italy.
  • Ishchenko Y; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Hernández D; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, VIC 3002, Australia; Department of Surgery, the University of Melbourne, Melbourne, VIC 3002, Australia; Department of Anatomy and Neuroscience, the University of Melbourne, Melbourne, VIC 3002, Australia.
  • Fazaludeen MF; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Eamen S; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Budia MG; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Fagerlund I; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Scoyni F; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Korhonen P; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Huber N; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Haapasalo A; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Hewitt AW; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, VIC 3002, Australia; Department of Surgery, the University of Melbourne, Melbourne, VIC 3002, Australia; School of Medicine, Menzies Institute for Medical Research, University of Tasmania, Hobart, VIC 7005, Australia
  • Vickers J; Wicking Dementia Research and Education Centre, University of Tasmania, Hobart, TAS 7000, Australia.
  • Smith GC; School of Chemistry and Molecular Bioscience, Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.
  • Oksanen M; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Graff C; Department NVS, Division of Neurogeriatrics, Karolinka Institutet, Stockholm 17176, Sweden; Theme Aging, Genetics Unit, Karolinska University Hospital-Solna, Stockholm 17176, Sweden.
  • Kanninen KM; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Lehtonen S; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland.
  • Propson N; Department of Molecular and Cell Biology and the Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.
  • Schwartz MP; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
  • Pébay A; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, VIC 3002, Australia; Department of Surgery, the University of Melbourne, Melbourne, VIC 3002, Australia; Department of Anatomy and Neuroscience, the University of Melbourne, Melbourne, VIC 3002, Australia.
  • Koistinaho J; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland; Neuroscience Center, University of Helsinki, Helsinki 00014, Finland.
  • Ooi L; School of Chemistry and Molecular Bioscience, Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.
  • Malm T; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70211, Finland. Electronic address: tarja.malm@uef.fi.
Stem Cell Reports ; 13(4): 669-683, 2019 10 08.
Article em En | MEDLINE | ID: mdl-31522977
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Diferenciação Celular / Precursor de Proteína beta-Amiloide / Microglia / Apolipoproteína E4 / Presenilina-1 / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Finlândia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Diferenciação Celular / Precursor de Proteína beta-Amiloide / Microglia / Apolipoproteína E4 / Presenilina-1 / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Finlândia