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Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.
Brouwer, Philip J M; Antanasijevic, Aleksandar; Berndsen, Zachary; Yasmeen, Anila; Fiala, Brooke; Bijl, Tom P L; Bontjer, Ilja; Bale, Jacob B; Sheffler, William; Allen, Joel D; Schorcht, Anna; Burger, Judith A; Camacho, Miguel; Ellis, Daniel; Cottrell, Christopher A; Behrens, Anna-Janina; Catalano, Marco; Del Moral-Sánchez, Iván; Ketas, Thomas J; LaBranche, Celia; van Gils, Marit J; Sliepen, Kwinten; Stewart, Lance J; Crispin, Max; Montefiori, David C; Baker, David; Moore, John P; Klasse, Per Johan; Ward, Andrew B; King, Neil P; Sanders, Rogier W.
Afiliação
  • Brouwer PJM; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Antanasijevic A; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • Berndsen Z; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • Yasmeen A; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, 10065, USA.
  • Fiala B; Department of Biochemistry, University of Washington, Seattle, Washington, 98195, USA.
  • Bijl TPL; Institute for Protein Design, University of Washington, Seattle, Washington, 98195, USA.
  • Bontjer I; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Bale JB; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Sheffler W; Department of Biochemistry, University of Washington, Seattle, Washington, 98195, USA.
  • Allen JD; Institute for Protein Design, University of Washington, Seattle, Washington, 98195, USA.
  • Schorcht A; Arzeda Corporation, Seattle, Washington, 98119, USA.
  • Burger JA; Department of Biochemistry, University of Washington, Seattle, Washington, 98195, USA.
  • Camacho M; Institute for Protein Design, University of Washington, Seattle, Washington, 98195, USA.
  • Ellis D; Biological Sciences and Institute of Life Sciences, University of Southampton, SO17 1BJ, Southampton, UK.
  • Cottrell CA; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Behrens AJ; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Catalano M; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Del Moral-Sánchez I; Department of Biochemistry, University of Washington, Seattle, Washington, 98195, USA.
  • Ketas TJ; Institute for Protein Design, University of Washington, Seattle, Washington, 98195, USA.
  • LaBranche C; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • van Gils MJ; Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, OX1 3QU, Oxford, UK.
  • Sliepen K; New England Biolabs, Inc., Ipswich, Massachussetts, 01938, USA.
  • Stewart LJ; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Crispin M; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Montefiori DC; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, 10065, USA.
  • Baker D; Department of Surgery, Duke University Medical Center, Durham, North Carolina, 27710, USA.
  • Moore JP; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Klasse PJ; Amsterdam UMC, Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, 1105AZ, The Netherlands.
  • Ward AB; Department of Biochemistry, University of Washington, Seattle, Washington, 98195, USA.
  • King NP; Institute for Protein Design, University of Washington, Seattle, Washington, 98195, USA.
  • Sanders RW; Biological Sciences and Institute of Life Sciences, University of Southampton, SO17 1BJ, Southampton, UK.
Nat Commun ; 10(1): 4272, 2019 09 19.
Article em En | MEDLINE | ID: mdl-31537780
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes / Antígenos Virais Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes / Antígenos Virais Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda