Combined Immunotherapy in Metastatic Melanoma with Unknown Primary.

Melanoma is skin cancer arising from melanocytes. It may metastasize to unusual areas of the body. Metastatic melanoma with unknown primary (MUP) is relatively uncommon. We present a case of MUP in a 55-year-old male, who underwent adjuvant treatment with combined immunotherapy and showed a good response. We report this case to alert fellow physicians that immunotherapy can be used in MUP with excellent outcomes.