Fluorescent schiff base probes for sequential detection of Al3+ and F- and cell imaging applications.
Spectrochim Acta A Mol Biomol Spectrosc
; 227: 117678, 2020 Feb 15.
Article
em En
| MEDLINE
| ID: mdl-31676151
ABSTRACT
Two novel Schiff-base fluorescent probers SQ and NQ based on 8-hydroxyquinoline moiety were designed and synthesized. The both probes were capable of binding with Al3+ by naked eye detection to produce a significant fluorescence enhancement response with a detection limit of 1.48â¯×â¯10-8 and 4.23â¯×â¯10-8â¯M, respectively. At the same time, the formed complexes SQ-Al3+ and NQ-Al3+ could sequentially detect F-, and the detection limits of F- were determined to be 1.64â¯×â¯10-7 and 3.58â¯×â¯10-8â¯M, respectively. The "off-on-off" fluorescence response process demonstrated that the binding were reversible. The probes were further successfully utilized to detect Al3+ and F- in vitro PC12â¯cells.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bases de Schiff
/
Imageamento Tridimensional
/
Alumínio
/
Corantes Fluorescentes
/
Flúor
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Spectrochim Acta A Mol Biomol Spectrosc
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China