State of the science on alternatives to animal testing and integration of testing strategies for food safety assessments: Workshop proceedings.
Regul Toxicol Pharmacol
; 110: 104515, 2020 Feb.
Article
em En
| MEDLINE
| ID: mdl-31705943
ABSTRACT
Rapidly evolving technological methods and mechanistic toxicological understanding have paved the way for new science-based approaches for the determination of chemical safety in support of advancing public health. Approaches including read-across, high-throughput screening, in silico models, and organ-on-a-chip technologies were addressed in a 2017 workshop focusing on how scientists can move effectively toward a vision for 21st century food safety assessments. The application of these alternative methods, the need for further development of standardized practices, and the interpretation and communication of results were addressed. Expert presentations encompassed regulatory, industry, and academic perspectives, and the workshop culminated in a panel discussion in which participants engaged experts about current issues pertaining to the application of alternative methods in toxicological testing for food safety assessments.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Testes de Toxicidade
/
Inocuidade dos Alimentos
/
Alternativas aos Testes com Animais
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Regul Toxicol Pharmacol
Ano de publicação:
2020
Tipo de documento:
Article