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Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents.
Póti, Ádám; Gyergyák, Hella; Németh, Eszter; Rusz, Orsolya; Tóth, Szilárd; Kovácsházi, Csenger; Chen, Dan; Szikriszt, Bernadett; Spisák, Sándor; Takeda, Shunichi; Szakács, Gergely; Szallasi, Zoltan; Richardson, Andrea L; Szüts, Dávid.
Afiliação
  • Póti Á; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Gyergyák H; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Németh E; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Rusz O; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Tóth S; Department of Oncotherapy, University of Szeged, Szeged, Hungary.
  • Kovácsházi C; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Chen D; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Szikriszt B; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Spisák S; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Takeda S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Szakács G; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Szallasi Z; Department of Radiation Genetics, Kyoto University Medical School, Kyoto, 606-8501, Japan.
  • Richardson AL; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudosok krt 2, Budapest, H-1117, Hungary.
  • Szüts D; Institute of Cancer Research, Medical University Vienna, Vienna, Austria.
Genome Biol ; 20(1): 240, 2019 11 14.
Article em En | MEDLINE | ID: mdl-31727117
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutagênese / Genes cdc / Reparo de DNA por Recombinação / Inibidores de Poli(ADP-Ribose) Polimerases / Variantes Farmacogenômicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Genome Biol Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Hungria
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutagênese / Genes cdc / Reparo de DNA por Recombinação / Inibidores de Poli(ADP-Ribose) Polimerases / Variantes Farmacogenômicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Genome Biol Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Hungria