Prophylactic <i>In Vivo</i> Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models.

Li, Chang; Course, Meredith M; McNeish, Iain A; Drescher, Charles W; Valdmanis, Paul N; Lieber, André

Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models.

Li, Chang; Course, Meredith M; McNeish, Iain A; Drescher, Charles W; Valdmanis, Paul N; Lieber, André.

Afiliação

Li C; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington.
Course MM; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington.
McNeish IA; Imperial College, London, United Kingdom.
Drescher CW; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Valdmanis PN; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington.
Lieber A; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington. lieber00@uw.edu.

Cancer Res ; 80(3): 549-560, 2020 02 01.

Article em En | MEDLINE | ID: mdl-31727629

Assuntos

Antígeno B7-H1/genética; Terapia Genética; Transplante de Células-Tronco Hematopoéticas; Células-Tronco Hematopoéticas/citologia; Neoplasias Mamárias Animais/terapia; MicroRNAs/genética; Neoplasias Ovarianas/terapia; Animais; Apoptose; Proliferação de Células; Terapia Combinada; Feminino; Células-Tronco Hematopoéticas/metabolismo; Humanos; Neoplasias Mamárias Animais/genética; Neoplasias Mamárias Animais/patologia; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Neoplasias Ovarianas/genética; Neoplasias Ovarianas/patologia; Células Tumorais Cultivadas; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Células-Tronco Hematopoéticas / Terapia Genética / Neoplasias Mamárias Animais / Transplante de Células-Tronco Hematopoéticas / MicroRNAs / Antígeno B7-H1 Limite: Animals / Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2020 Tipo de documento: Article

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