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Brain cell type-specific enhancer-promoter interactome maps and disease-risk association.
Nott, Alexi; Holtman, Inge R; Coufal, Nicole G; Schlachetzki, Johannes C M; Yu, Miao; Hu, Rong; Han, Claudia Z; Pena, Monique; Xiao, Jiayang; Wu, Yin; Keulen, Zahara; Pasillas, Martina P; O'Connor, Carolyn; Nickl, Christian K; Schafer, Simon T; Shen, Zeyang; Rissman, Robert A; Brewer, James B; Gosselin, David; Gonda, David D; Levy, Michael L; Rosenfeld, Michael G; McVicker, Graham; Gage, Fred H; Ren, Bing; Glass, Christopher K.
Afiliação
  • Nott A; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Holtman IR; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Coufal NG; Section Molecular Neurobiology, Department of Biomedical Sciences of Cells & Systems, University Medical Center Groningen, University of Groningen, 9713 AV Groningen, the Netherlands.
  • Schlachetzki JCM; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Yu M; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Hu R; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Han CZ; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Pena M; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
  • Xiao J; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Wu Y; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Keulen Z; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Pasillas MP; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • O'Connor C; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Nickl CK; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Schafer ST; Flow Cytometry Core Facility, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Shen Z; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Rissman RA; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Brewer JB; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gosselin D; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gonda DD; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • Levy ML; Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA.
  • Rosenfeld MG; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA.
  • McVicker G; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gage FH; Centre de Recherche du Centre Hospitalier Universitaire de Québec-Université Laval, Département de Médecine Moléculaire, Faculté de Médecine, Université Laval, Québec G1V 4G2, Canada.
  • Ren B; Department of Neurosurgery, University of California, San Diego-Rady Children's Hospital, San Diego, CA 92123, USA.
  • Glass CK; Department of Neurosurgery, University of California, San Diego-Rady Children's Hospital, San Diego, CA 92123, USA.
Science ; 366(6469): 1134-1139, 2019 11 29.
Article em En | MEDLINE | ID: mdl-31727856
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / Encéfalo / Proteínas Nucleares / Elementos Facilitadores Genéticos / Regiões Promotoras Genéticas / Microglia / Proteínas Supressoras de Tumor / Proteínas Adaptadoras de Transdução de Sinal / Doença de Alzheimer Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Science Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / Encéfalo / Proteínas Nucleares / Elementos Facilitadores Genéticos / Regiões Promotoras Genéticas / Microglia / Proteínas Supressoras de Tumor / Proteínas Adaptadoras de Transdução de Sinal / Doença de Alzheimer Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Science Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos