Respiratory motion-corrected, compressively sampled dynamic MR image reconstruction by exploiting multiple sparsity constraints and phase correlation-based data binning.

ABSTRACT

INTRODUCTION: Cardiac magnetic resonance imaging (cMRI) is a standard method that is clinically used to evaluate the function of the human heart. Respiratory motion during a cMRI scan causes blurring artefacts in the reconstructed images. In conventional MRI, breath holding is used to avoid respiratory motion artefacts, which may be difficult for cardiac patients. MATERIALS AND METHODS: This paper proposes a method in which phase correlation-based binning, followed by image registration-based sparsity along with spatio-temporal sparsity, is incorporated into the standard low rank + sparse (L+S) reconstruction for free-breathing cardiac cine MRI. The proposed method is validated on clinical data and simulated free-breathing cardiac cine data for different acceleration factors (AFs). The reconstructed images are analysed using visual assessment, artefact power (AP) and root-mean-square error (RMSE). The results of the proposed method are compared with the contemporary motion-corrected compressed sensing (MC-CS) method given in the literature. RESULTS: Our results show that the proposed method successfully reconstructs the motion-corrected images from respiratory motion-corrupted, compressively sampled cardiac cine MR data, e.g., there is 26% and 24% improvement in terms of AP and RMSE values, respectively, at AF = 4 and 20% and 16.04% improvement in terms of AP and RMSE values, respectively, at AF = 8 in the reconstruction results from the proposed method for the cardiac phantom cine data. CONCLUSION: The proposed method achieves significant improvement in the AP and RMSE values at different AFs for both the phantom and in vivo data.