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Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles.
Dai, Zeshu; Tian, Qingqiang; Li, Yanwu; Shang, Suqin; Luo, Wen; Wang, Xuetong; Li, Dan; Zhang, Ying; Li, Zhiyao; Yuan, Jianyong.
Afiliação
  • Dai Z; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Tian Q; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Li Y; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Shang S; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Luo W; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Wang X; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Li D; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Zhang Y; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Li Z; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
  • Yuan J; Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
Molecules ; 24(23)2019 Nov 20.
Article em En | MEDLINE | ID: mdl-31757097
ABSTRACT
An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Heterocíclicos / Imidazóis Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Heterocíclicos / Imidazóis Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China