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microRNA overexpression in slow transit constipation leads to reduced NaV1.5 current and altered smooth muscle contractility.
Mazzone, Amelia; Strege, Peter R; Gibbons, Simon J; Alcaino, Constanza; Joshi, Vikram; Haak, Andrew J; Tschumperlin, Daniel J; Bernard, Cheryl E; Cima, Robert R; Larson, David W; Chua, Heidi K; Graham, Rondell P; El Refaey, Mona; Mohler, Peter J; Hayashi, Yujiro; Ordog, Tamas; Calder, Stefan; Du, Peng; Farrugia, Gianrico; Beyder, Arthur.
Afiliação
  • Mazzone A; Enteric NeuroScience Program (ENSP), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Strege PR; Enteric NeuroScience Program (ENSP), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Gibbons SJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
  • Alcaino C; Enteric NeuroScience Program (ENSP), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Joshi V; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
  • Haak AJ; Enteric NeuroScience Program (ENSP), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Tschumperlin DJ; Enteric NeuroScience Program (ENSP), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Bernard CE; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
  • Cima RR; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
  • Larson DW; Enteric NeuroScience Program (ENSP), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Chua HK; Department of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota, USA.
  • Graham RP; Department of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota, USA.
  • El Refaey M; Department of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota, USA.
  • Mohler PJ; Department of Pathology, Mayo Clinic, Rochester, Minnesota, USA.
  • Hayashi Y; Departments of Physiology and Cell Biology, The Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Ordog T; Department of Internal Medicine, The Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Calder S; Departments of Physiology and Cell Biology, The Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Du P; Enteric NeuroScience Program (ENSP), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Farrugia G; Enteric NeuroScience Program (ENSP), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Beyder A; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Gut ; 69(5): 868-876, 2020 05.
Article em En | MEDLINE | ID: mdl-31757880
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Constipação Intestinal / MicroRNAs / Proteínas Associadas aos Microtúbulos / Contração Muscular Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Gut Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Constipação Intestinal / MicroRNAs / Proteínas Associadas aos Microtúbulos / Contração Muscular Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Gut Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos