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Identification of Reg3ß-producing cells using IL-22-stimulated enteroids.
Sato, Mika; Inaba, Akihiko; Iwatsuki, Ken; Saito, Yuki; Tadaishi, Miki; Shimizu, Makoto; Kobayashi-Hattori, Kazuo.
Afiliação
  • Sato M; Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan.
  • Inaba A; Department of Nutritional Science and Food Safety, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan.
  • Iwatsuki K; Department of Nutritional Science and Food Safety, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan.
  • Saito Y; Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan.
  • Tadaishi M; Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan.
  • Shimizu M; Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan.
  • Kobayashi-Hattori K; Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan.
Biosci Biotechnol Biochem ; 84(3): 594-597, 2020 Mar.
Article em En | MEDLINE | ID: mdl-31760857
ABSTRACT
Reg3ß, a lectin, displays antibacterial activity. This study investigated Reg3ß-expressing cells using IL-22-stimulated enteroids. IL-22 stimulation elevated the mRNA and protein levels of Reg3ß. IL-22 also increased the mRNA levels of CD133 (a transit-amplifying cell marker) and lysozyme (a Paneth cell marker). Immunohistochemistry showed partial colocalization of Reg3ß- and lysozyme-positive cells, suggesting that Paneth cells are one of Reg3ß-producing cells.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Celulas de Paneth / Lectinas Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Celulas de Paneth / Lectinas Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão