Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice.

Wang, Chao; Zhang, Lu; Ndong, Jean De La Croix; Hettinghouse, Aubryanna; Sun, Guodong; Chen, Changhong; Zhang, Chen; Liu, Ronghan; Liu, Chuan-Ju

Wang, Chao; Zhang, Lu; Ndong, Jean De La Croix; Hettinghouse, Aubryanna; Sun, Guodong; Chen, Changhong; Zhang, Chen; Liu, Ronghan; Liu, Chuan-Ju.

Afiliação

Wang C; Department of Orthopaedic Surgery, New York University School of Medicine, New York, NY, 10003, USA.
Zhang L; Department of Spine Surgery, The Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Ndong JC; Department of Spine Surgery, The Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Hettinghouse A; Department of Orthopaedic Surgery, New York University School of Medicine, New York, NY, 10003, USA.
Sun G; Department of Orthopaedic Surgery, New York University School of Medicine, New York, NY, 10003, USA.
Chen C; Department of Orthopaedic Surgery, New York University School of Medicine, New York, NY, 10003, USA.
Zhang C; Department of Orthopaedic Surgery, New York University School of Medicine, New York, NY, 10003, USA.
Liu R; Department of Orthopaedic Surgery, New York University School of Medicine, New York, NY, 10003, USA.
Liu CJ; Department of Orthopaedic Surgery, New York University School of Medicine, New York, NY, 10003, USA.

J Neuroinflammation ; 16(1): 238, 2019 Nov 27.

Article em En | MEDLINE | ID: mdl-31775776

Assuntos

Apoptose/fisiologia; Inflamação/metabolismo; Progranulinas/metabolismo; Traumatismos da Medula Espinal/metabolismo; Animais; Citocinas/metabolismo; Feminino; Inflamação/genética; Camundongos; Camundongos Knockout; Óxido Nítrico Sintase Tipo II/metabolismo; Progranulinas/genética; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Recuperação de Função Fisiológica/fisiologia; Traumatismos da Medula Espinal/genética; Regulação para Cima; Proteína X Associada a bcl-2/metabolismo

Palavras-chave

Apoptosis; Inflammation; Progranulin; Spinal cord injury

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismos da Medula Espinal / Apoptose / Progranulinas / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Neuroinflammation Assunto da revista: NEUROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google