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4-MeO-PCP and 3-MeO-PCMo, new dissociative drugs, produce rewarding and reinforcing effects through activation of mesolimbic dopamine pathway and alteration of accumbal CREB, deltaFosB, and BDNF levels.
Abiero, Arvie; Botanas, Chrislean Jun; Custodio, Raly James; Sayson, Leandro Val; Kim, Mikyung; Lee, Hyun Jun; Kim, Hee Jin; Lee, Kun Won; Jeong, Youngdo; Seo, Joung-Wook; Ryu, In Soo; Lee, Yong Sup; Cheong, Jae Hoon.
Afiliação
  • Abiero A; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Botanas CJ; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Custodio RJ; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Sayson LV; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Kim M; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Lee HJ; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Kim HJ; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Lee KW; Medicinal Chemistry Laboratory, Department of Pharmacy & Department of Life and Nanopharmaceutical Sciences, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul, 02447, Republic of Korea.
  • Jeong Y; Medicinal Chemistry Laboratory, Department of Pharmacy & Department of Life and Nanopharmaceutical Sciences, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul, 02447, Republic of Korea.
  • Seo JW; Center for Safety Pharmacology, Korea Institute of Toxicology, Daejeon, 305-343, Republic of Korea.
  • Ryu IS; Center for Safety Pharmacology, Korea Institute of Toxicology, Daejeon, 305-343, Republic of Korea.
  • Lee YS; Medicinal Chemistry Laboratory, Department of Pharmacy & Department of Life and Nanopharmaceutical Sciences, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul, 02447, Republic of Korea. kyslee@khu.ac.kr.
  • Cheong JH; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarangro, Nowon-gu, Seoul, 01795, Republic of Korea. cheongjh@syu.ac.kr.
Psychopharmacology (Berl) ; 237(3): 757-772, 2020 Mar.
Article em En | MEDLINE | ID: mdl-31828394
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenciclidina / Dopamina / Morfolinas / Proteínas Proto-Oncogênicas c-fos / Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico / Fator Neurotrófico Derivado do Encéfalo / Núcleo Accumbens Limite: Animals Idioma: En Revista: Psychopharmacology (Berl) Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenciclidina / Dopamina / Morfolinas / Proteínas Proto-Oncogênicas c-fos / Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico / Fator Neurotrófico Derivado do Encéfalo / Núcleo Accumbens Limite: Animals Idioma: En Revista: Psychopharmacology (Berl) Ano de publicação: 2020 Tipo de documento: Article