The Association of Serum Vitamin D Level With the Severity of Dry Eye Parameters in Primary Sjögren Syndrome.
Cornea
; 39(6): 702-705, 2020 Jun.
Article
em En
| MEDLINE
| ID: mdl-31868853
ABSTRACT
PURPOSE:
To analyze the relationship between serum 25(OH)D3 level and dry eye parameters in primary Sjögren syndrome (SS).METHODS:
This study included 74 eyes of 74 patients diagnosed with primary SS. Dry eye parameters included tear breakup time, Schirmer I value, corneal staining score, conjunctival staining score, and Ocular Surface Disease Index. The serum concentration of 25(OH)D3 was evaluated.RESULTS:
The mean serum 25(OH)D3 level was 20.4 ± 8.0 ng/mL. There were strong negative correlations between serum 25(OH)D3 level and corneal staining score (P < 0.001, r = -0.446) and conjunctival staining score (P < 0.001, r = -0.455). The Schirmer I value and tear breakup time showed significant positive correlations with serum 25(OH)D3 level (P = 0.038, r = 0.261 and P = 0.003, r = 0.352, respectively). The Ocular Surface Disease Index did not show any significant correlation with serum 25(OH)D3 level.CONCLUSIONS:
This study demonstrates that serum 25(OH)D3 level might be associated with dry eye severity in primary SS.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lágrimas
/
Vitamina D
/
Síndromes do Olho Seco
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Síndrome de Sjogren
/
Túnica Conjuntiva
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cornea
Ano de publicação:
2020
Tipo de documento:
Article