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MiR-202-5p attenuates neurological deficits and neuronal injury in MCAO model rats and OGD-induced injury in Neuro-2a cells by targeting eIF4E-mediated induction of autophagy and inhibition of Akt/GSK-3ß pathway.
Li, Bing; Huang, Zhi; Meng, Ju; Yu, Wenfeng; Yang, Hua.
Afiliação
  • Li B; Department of Neurosurgery, The Affiliated Hospital of Gui Zhou Medical University, Guiyang, 550004, China; Department of Ophthalmology, The Affiliated Hospital of Gui Zhou Medical University, Guiyang, 550004, China; Key Laboratory of Endemic and Ethnic Diseases, Key Laboratory of Medical Molecular
  • Huang Z; School of Basic Medical Sciences, Gui Zhou Medical University, Guiyang, 550025, China; Department of Interventional Radiology, The Affiliated Cancer Hospital of Guizhou Medical University, Guiyang, 550005, China; Department of Interventional Radiology, The Second Affiliated Hospital, Guizhou Medical
  • Meng J; Department of Vascular Surgery, The Affiliated Hospital of Gui Zhou Medical University, Guiyang, 550004, China.
  • Yu W; Key Laboratory of Endemic and Ethnic Diseases, Key Laboratory of Medical Molecular Biology in Guizhou Medical University, Guiyang, 550002, China. Electronic address: wenfengyu21@sohu.com.
  • Yang H; Department of Neurosurgery, The Affiliated Hospital of Gui Zhou Medical University, Guiyang, 550004, China. Electronic address: yhmed33@aliyun.com.
Mol Cell Probes ; 51: 101497, 2020 06.
Article em En | MEDLINE | ID: mdl-31877332

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Infarto da Artéria Cerebral Média / Fator de Iniciação 4E em Eucariotos / MicroRNAs / Proteínas Proto-Oncogênicas c-akt / Autofagossomos / Glicogênio Sintase Quinase 3 beta / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Mol Cell Probes Assunto da revista: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Infarto da Artéria Cerebral Média / Fator de Iniciação 4E em Eucariotos / MicroRNAs / Proteínas Proto-Oncogênicas c-akt / Autofagossomos / Glicogênio Sintase Quinase 3 beta / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Mol Cell Probes Assunto da revista: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article