Adamantinomatous craniopharyngioma: moving toward targeted therapies.

Hengartner, Astrid C; Prince, Eric; Vijmasi, Trinka; Hankinson, Todd C

Hengartner, Astrid C; Prince, Eric; Vijmasi, Trinka; Hankinson, Todd C.

Afiliação

Hengartner AC; 1Pediatric Neurosurgery, Children's Hospital Colorado, University of Colorado School of Medicine; and.
Prince E; 1Pediatric Neurosurgery, Children's Hospital Colorado, University of Colorado School of Medicine; and.
Vijmasi T; 1Pediatric Neurosurgery, Children's Hospital Colorado, University of Colorado School of Medicine; and.
Hankinson TC; 1Pediatric Neurosurgery, Children's Hospital Colorado, University of Colorado School of Medicine; and.

Neurosurg Focus ; 48(1): E7, 2020 01 01.

Article em En | MEDLINE | ID: mdl-31896087

Assuntos

Craniofaringioma/metabolismo; Craniofaringioma/terapia; Neoplasias Hipofisárias/metabolismo; Neoplasias Hipofisárias/terapia; Antígeno B7-H1/metabolismo; Craniofaringioma/genética; Proteínas Hedgehog/metabolismo; Humanos; Recidiva Local de Neoplasia/metabolismo; Neoplasias Hipofisárias/genética; Receptor de Morte Celular Programada 1/metabolismo; Qualidade de Vida; Transdução de Sinais/fisiologia

Palavras-chave

ACP = adamantinomatous craniopharyngioma; ERK = extracellular signalregulated kinase; IFN = interferon; IL-6 = interleukin 6; MAPK = mitogen-activated protein kinase; MEK = mitogen extracellular kinase; PD-1 = programmed cell death protein 1; PD-L1 = programmed cell death protein ligand 1; SHH = Sonic Hedgehog; TGF-α = transforming growth factorα; adamantinomatous craniopharyngioma; childhood craniopharyngioma; genetically engineered mouse model; targeted therapies

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Hipofisárias / Craniofaringioma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Neurosurg Focus Assunto da revista: NEUROCIRURGIA Ano de publicação: 2020 Tipo de documento: Article

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