Mesenchymal stem cells-derived exosomes improve pregnancy outcome through inducing maternal tolerance to the allogeneic fetus in abortion-prone mating mouse.

Xiang, Yan-Jie; Hou, Yan-Yan; Yan, Hong-Li; Liu, Hui; Ge, Yan-Xin; Chen, Na; Xiang, Jian-Feng; Hao, Cui-Fang

Xiang, Yan-Jie; Hou, Yan-Yan; Yan, Hong-Li; Liu, Hui; Ge, Yan-Xin; Chen, Na; Xiang, Jian-Feng; Hao, Cui-Fang.

Afiliação

Xiang YJ; School of Medicine, Shandong University, Jinan, Shandong Province, People's Republic of China.
Hou YY; Reproductive Medicine Center, The Affiliated Changhai Hospital of China Naval Military Medical University, Shanghai, People's Republic of China.
Yan HL; Maternity Department of International Maternal and Child Peace Hospital, The Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Liu H; Reproductive Medicine Center, The Affiliated Changhai Hospital of China Naval Military Medical University, Shanghai, People's Republic of China.
Ge YX; Department of Reproductive Medicine, People's Hospital of Rizhao, Rizhao, Shandong, People's Republic of China.
Chen N; Department of Reproductive Medicine, People's Hospital of Rizhao, Rizhao, Shandong, People's Republic of China.
Xiang JF; Department of Obstetrics, Traditional Chinese Medicine Hospital of The West Coast of Qingdao New District, Qingdao, Shandong, People's Republic of China.
Hao CF; Department of Intervention, Shanghai Fengxian District Central Hospital, Shanghai, People's Republic of China.

Kaohsiung J Med Sci ; 36(5): 363-370, 2020 May.

Article em En | MEDLINE | ID: mdl-31943723

Assuntos

Aborto Habitual/imunologia; Exossomos/metabolismo; Feto/imunologia; Tolerância Imunológica; Células-Tronco Mesenquimais/metabolismo; Resultado da Gravidez; Comportamento Sexual Animal; Aborto Habitual/genética; Animais; Feminino; Imunofenotipagem; Macrófagos/metabolismo; Troca Materno-Fetal; Camundongos; MicroRNAs/genética; MicroRNAs/metabolismo; Gravidez; Linfócitos T/metabolismo

Palavras-chave

exosome; mesenchymal stem cell; recurrent pregnancy loss

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comportamento Sexual Animal / Resultado da Gravidez / Aborto Habitual / Exossomos / Feto / Células-Tronco Mesenquimais / Tolerância Imunológica Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Revista: Kaohsiung J Med Sci Assunto da revista: MEDICINA Ano de publicação: 2020 Tipo de documento: Article

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