Critical redundant functions of the adapters Grb2 and Gads in platelet (hem)ITAM signaling in mice.

Vögtle, Timo; Baig, Ayesha A; Volz, Julia; Duchow, Timothy B; Pleines, Irina; Dütting, Sebastian; Nitschke, Lars; Watson, Stephen P; Nieswandt, Bernhard

Vögtle, Timo; Baig, Ayesha A; Volz, Julia; Duchow, Timothy B; Pleines, Irina; Dütting, Sebastian; Nitschke, Lars; Watson, Stephen P; Nieswandt, Bernhard.

Afiliação

Vögtle T; Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center, University of Würzburg , Würzburg, Germany.
Baig AA; Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center, University of Würzburg , Würzburg, Germany.
Volz J; Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center, University of Würzburg , Würzburg, Germany.
Duchow TB; Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center, University of Würzburg , Würzburg, Germany.
Pleines I; Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center, University of Würzburg , Würzburg, Germany.
Dütting S; Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center, University of Würzburg , Würzburg, Germany.
Nitschke L; Department of Biology, Division of Genetics, University of Erlangen , Erlangen, Germany.
Watson SP; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham , Birmingham, UK.
Nieswandt B; Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham , The Midlands, UK.

Platelets ; 31(6): 801-811, 2020 Aug 17.

Article em En | MEDLINE | ID: mdl-31948362

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Proteína Adaptadora GRB2/metabolismo; Motivo de Ativação do Imunorreceptor Baseado em Tirosina/genética; Animais; Humanos; Camundongos; Transdução de Sinais

Palavras-chave

Adapter proteins; ITAM; hemostasis; mice; signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Adaptadoras de Transdução de Sinal / Proteína Adaptadora GRB2 / Motivo de Ativação do Imunorreceptor Baseado em Tirosina Limite: Animals / Humans Idioma: En Revista: Platelets Assunto da revista: HEMATOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

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