Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload.

Mohammadzadeh, Naiyereh; Melleby, Arne Olav; Palmero, Sheryl; Sjaastad, Ivar; Chakravarti, Shukti; Engebretsen, Kristin V T; Christensen, Geir; Lunde, Ida G; Tønnessen, Theis

Mohammadzadeh, Naiyereh; Melleby, Arne Olav; Palmero, Sheryl; Sjaastad, Ivar; Chakravarti, Shukti; Engebretsen, Kristin V T; Christensen, Geir; Lunde, Ida G; Tønnessen, Theis.

Afiliação

Mohammadzadeh N; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Melleby AO; KG Jebsen Center for Cardiac Research and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Palmero S; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Sjaastad I; KG Jebsen Center for Cardiac Research and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Chakravarti S; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Engebretsen KVT; KG Jebsen Center for Cardiac Research and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Christensen G; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Lunde IG; KG Jebsen Center for Cardiac Research and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Tønnessen T; Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

Cardiology ; 145(3): 187-198, 2020.

Article em En | MEDLINE | ID: mdl-31968347

Assuntos

Insuficiência Cardíaca/metabolismo; Ventrículos do Coração/metabolismo; Hipertrofia Ventricular Esquerda/metabolismo; Lumicana/fisiologia; Miofibroblastos/metabolismo; Animais; Colágeno/metabolismo; Modelos Animais de Doenças; Ecocardiografia; Matriz Extracelular/metabolismo; Ventrículos do Coração/patologia; Lumicana/genética; Masculino; Camundongos; Camundongos Knockout; Miofibroblastos/patologia; Remodelação Ventricular

Palavras-chave

Aortic banding; Cardiac fibrosis; Cardiac remodeling; Lumican

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipertrofia Ventricular Esquerda / Miofibroblastos / Lumicana / Insuficiência Cardíaca / Ventrículos do Coração Limite: Animals Idioma: En Revista: Cardiology Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Noruega

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