Gingival Papillomatosis as the Oral Sign of Cowden Syndrome: A Case Report.
Acta Dermatovenerol Croat
; 27(4): 260-264, 2019 Dec.
Article
em En
| MEDLINE
| ID: mdl-31969239
ABSTRACT
Cowden syndrome (CS) is a rare autosomal dominant, hereditary, multiorgan disease with higher risk for malignancies (breast, thyroid, endometrium). Mucocutaneous lesions occur in 90% of cases and are characterized by facial trichilemmomas, oral mucosal papillomas, and benign acral keratoses. We present the case of a 39-year-old female patient with the chief complaint of "white spots" on the upper and lower attached gingiva accompanied with skin changes on the face, hands, and soles. The patient's family medical history revealed that her mother had an endometrial polyp and the sister had thyroid cancer. In the patient's medical personal history she reported follicular thyroid adenoma, thyroid abnormalities (i.e. lymphocytic thyroiditis), fibrocystic changes and juvenile breast papillomatosis, lipoma, multiple fibromas, and genitourinary tumors. Based on extensive family and personal medical history, physical examination and histopathological findings, diagnostic criteria were fulfilled for the diagnosis of Cowden syndrome.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Papiloma
/
Síndrome do Hamartoma Múltiplo
/
Neoplasias Gengivais
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Acta Dermatovenerol Croat
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2019
Tipo de documento:
Article