Your browser doesn't support javascript.
loading
Modified BODE Index to Predict Mortality in Individuals With COPD: The Role of 4-Min Step Test.
Vieira, Elaine B; Degani-Costa, Luiza H; Amorim, Beatriz C; Oliveira, Lígia B; Miranda-Silva, Talita; Sperandio, Priscila Ca; Medeiros, Wladimir M; Arbex, Flávio F; Ramos, Roberta P; Nery, Luiz E.
Afiliação
  • Vieira EB; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Degani-Costa LH; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Amorim BC; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Oliveira LB; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Miranda-Silva T; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Sperandio PC; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Medeiros WM; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Arbex FF; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
  • Ramos RP; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil. robertapulcheri@gmail.com.
  • Nery LE; All authors are affiliated with Pulmonary Function and Exercise Physiology Unit, Division of Respiratory Diseases, Department of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
Respir Care ; 65(7): 977-983, 2020 Jul.
Article em En | MEDLINE | ID: mdl-31992673
BACKGROUND: The BODE (body mass index, air-flow obstruction, dyspnea, exercise capacity) index is a composite prognostic marker that predicts mortality in COPD. It includes body mass index, air-flow obstruction, dyspnea score, and exercise capacity by using the 6-min walk distance. However, a 30-m-long corridor is necessary to perform the test and this limits its use in clinical practice. Step tests may elicit distinct physiologic responses compared with the 6-min walk test but are easy to perform in the office setting. We sought to investigate whether a 4-min step test would be a suitable surrogate of the 6-min walk test, in a modified BODE step index (simplified BODE index), to predict mortality in COPD. METHODS: Individuals with COPD performed a self-paced 4-min step test, and the simplified BODE index was calculated by replacing the 6-min walk distance by the number of steps climbed. Cutoff values were determined by receiver operating characteristic curve analysis as follows: score 0 for >60 steps; score 1 for 50-60 steps; score 2 for 40-49 steps; and score 3 for <40 steps. RESULTS: A total of 186 individuals with COPD were enrolled from 2011 to 2016 (60% males; mean ± SD age, 65 ± 9 y; mean ± SD FEV1, 50 ± 17 L). There were 36 deaths among the study cohort. The simplified BODE index was a prognostic marker, independent of cardiovascular comorbidities and oxygen desaturation (HR 1.12, confidence interval (CI) [1.03-1.22]). Individuals with simplified BODE index scores ≥ 7 were at higher risk of death from any cause (P < .001, log-rank test). CONCLUSIONS: This was the first study, to our knowledge, to show that the 4-min step test as a surrogate of exercise capacity in the BODE index (simplified BODE index) is an independent predictor of mortality in COPD and may help to spread its use among practicing physicians.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Massa Corporal / Tolerância ao Exercício / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Respir Care Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Massa Corporal / Tolerância ao Exercício / Doença Pulmonar Obstrutiva Crônica Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Respir Care Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil