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Targeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo.
Du, Guifang; Wang, Jing; Zhang, Ting; Ding, Qiang; Jia, Xiaodong; Zhao, Xueke; Dong, Jinke; Yang, Xinrui; Lu, Shanshan; Zhang, Cuihong; Liu, Ze; Zeng, Zhen; Safadi, Rifaat; Qi, Ruizhao; Zhao, Xin; Hong, Zhixian; Lu, Yinying.
Afiliação
  • Du G; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Wang J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
  • Zhang T; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Ding Q; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Jia X; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Zhao X; Guizhou Medical University, Guizhou, China.
  • Dong J; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Yang X; Guizhou Medical University, Guizhou, China.
  • Lu S; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Zhang C; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Liu Z; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Zeng Z; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Safadi R; Comprehensive Liver Cancer Centre, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Qi R; Hadassah Medical Organization, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
  • Zhao X; Department of Hepatobiliary surgery, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Hong Z; Department of Hepatobiliary surgery, the Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Lu Y; Department of Hepatobiliary surgery, the Fifth Medical Center of PLA General Hospital, Beijing, China.
Cell Death Dis ; 11(2): 118, 2020 02 12.
Article em En | MEDLINE | ID: mdl-32051399

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Inibidores de Proteínas Quinases / Benzodioxóis / Proteínas Proto-Oncogênicas c-fyn / Células Estreladas do Fígado / Doença Hepática Induzida por Substâncias e Drogas / Fígado / Cirrose Hepática Experimental Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cell Death Dis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Inibidores de Proteínas Quinases / Benzodioxóis / Proteínas Proto-Oncogênicas c-fyn / Células Estreladas do Fígado / Doença Hepática Induzida por Substâncias e Drogas / Fígado / Cirrose Hepática Experimental Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cell Death Dis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China