A Bivalent, Spherical Virus-Like Particle Vaccine Enhances Breadth of Immune Responses against Pathogenic Ebola Viruses in Rhesus Macaques.

Singh, Karnail; Marasini, Bishal; Chen, Xuemin; Ding, Lingmei; Wang, Jaang-Jiun; Xiao, Peng; Villinger, Francois; Spearman, Paul

Singh, Karnail; Marasini, Bishal; Chen, Xuemin; Ding, Lingmei; Wang, Jaang-Jiun; Xiao, Peng; Villinger, Francois; Spearman, Paul.

Afiliação

Singh K; Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA Karnail.Singh@cchmc.org.
Marasini B; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Chen X; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Ding L; Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Wang JJ; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Xiao P; Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Villinger F; Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Spearman P; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

J Virol ; 94(9)2020 04 16.

Article em En | MEDLINE | ID: mdl-32075939

Assuntos

Vacinas contra Ebola/imunologia; Ebolavirus/imunologia; Doença pelo Vírus Ebola/imunologia; África Ocidental; Animais; Anticorpos Neutralizantes/imunologia; Anticorpos Antivirais/imunologia; Modelos Animais de Doenças; Feminino; Glicoproteínas/imunologia; Imunização; Macaca mulatta; Masculino; Vacinação; Vacinas Atenuadas; Vacinas de Partículas Semelhantes a Vírus/imunologia; Proteínas do Envelope Viral/imunologia; Vacinas Virais/imunologia

Palavras-chave

Bundibugyo virus; Ebola glycoprotein; Ebola vaccine; Ebola virus; Ebola virus disease; Marburg virus; Sudan virus; Tai Forest virus; virus-like particles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença pelo Vírus Ebola / Vacinas contra Ebola / Ebolavirus Limite: Animals País/Região como assunto: Africa Idioma: En Revista: J Virol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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