RGD peptide grafted polybutylene adipate-co-terephthalate/gelatin electrospun nanofibers loaded with a matrix metalloproteinase inhibitor drug for alleviating of wounds: an in vitro/in vivo study.

Varshosaz, Jaleh; Arabloo, Khatereh; Sarrami, Nasim; Ghassami, Erfaneh; Yazdani Kachouei, Emadeddin; Kouhi, Monireh; Jahanian-Najafabadi, Ali

RGD peptide grafted polybutylene adipate-co-terephthalate/gelatin electrospun nanofibers loaded with a matrix metalloproteinase inhibitor drug for alleviating of wounds: an in vitro/in vivo study.

Varshosaz, Jaleh; Arabloo, Khatereh; Sarrami, Nasim; Ghassami, Erfaneh; Yazdani Kachouei, Emadeddin; Kouhi, Monireh; Jahanian-Najafabadi, Ali.

Afiliação

Varshosaz J; Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Arabloo K; Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Sarrami N; Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Ghassami E; Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Yazdani Kachouei E; Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Kouhi M; Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Jahanian-Najafabadi A; Department of Biotechnology, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.

Drug Dev Ind Pharm ; 46(3): 484-497, 2020 Mar.

Article em En | MEDLINE | ID: mdl-32077331

Assuntos

Doxiciclina/administração & dosagem; Inibidores de Metaloproteinases de Matriz/administração & dosagem; Nanofibras; Cicatrização/efeitos dos fármacos; Animais; Antibacterianos/administração & dosagem; Antibacterianos/farmacologia; Bandagens; Linhagem Celular; Doxiciclina/farmacologia; Liberação Controlada de Fármacos; Fibroblastos/efeitos dos fármacos; Fibroblastos/metabolismo; Gelatina/química; Masculino; Inibidores de Metaloproteinases de Matriz/farmacologia; Camundongos; Oligopeptídeos/química; Poliésteres/química; Pseudomonas aeruginosa/efeitos dos fármacos; Ratos; Ratos Wistar; Staphylococcus aureus/efeitos dos fármacos

Palavras-chave

PBAT/gelatin nanofibrous membranes; RGD peptide; double needles electrospinning; doxycycline; wound healing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cicatrização / Doxiciclina / Nanofibras / Inibidores de Metaloproteinases de Matriz Limite: Animals Idioma: En Revista: Drug Dev Ind Pharm Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Irã

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