Chikungunya Virus Evades Antiviral CD8<sup>+</sup> T Cell Responses To Establish Persistent Infection in Joint-Associated Tissues.

Davenport, Bennett J; Bullock, Christopher; McCarthy, Mary K; Hawman, David W; Murphy, Kenneth M; Kedl, Ross M; Diamond, Michael S; Morrison, Thomas E

Chikungunya Virus Evades Antiviral CD8⁺ T Cell Responses To Establish Persistent Infection in Joint-Associated Tissues.

Davenport, Bennett J; Bullock, Christopher; McCarthy, Mary K; Hawman, David W; Murphy, Kenneth M; Kedl, Ross M; Diamond, Michael S; Morrison, Thomas E.

Afiliação

Davenport BJ; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Bullock C; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
McCarthy MK; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Hawman DW; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Murphy KM; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Kedl RM; Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, Missouri, USA.
Diamond MS; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Morrison TE; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

J Virol ; 94(9)2020 04 16.

Article em En | MEDLINE | ID: mdl-32102875

Assuntos

Febre de Chikungunya/imunologia; Vírus Chikungunya/metabolismo; Articulações/virologia; Imunidade Adaptativa/imunologia; Transferência Adotiva/métodos; Animais; Anticorpos Antivirais/imunologia; Antivirais/uso terapêutico; Artrite/virologia; Linfócitos T CD8-Positivos/imunologia; Linfócitos T CD8-Positivos/virologia; Febre de Chikungunya/metabolismo; Vírus Chikungunya/patogenicidade; Vírus Chikungunya/fisiologia; Modelos Animais de Doenças; Epitopos de Linfócito T/imunologia; Feminino; Imunização; Articulações/imunologia; Lectinas Tipo C; Masculino; Camundongos; Receptores Mitogênicos

Palavras-chave

CD8 T cell; alphavirus; chikungunya virus; viral persistence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Febre de Chikungunya / Articulações Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: J Virol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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